West Plains
Shop now
High Profile Cannabis Shop

West Plains

1391 Mitchell Rd, West Plains, MO 65775
(417) 596-9086
Open until 10:00pm today
All hours
Shop Now
View All Locations

Offered at High Profile West Plains

In-store Shopping

Drop in anytime

In-store Pickup

Reserve online

Drive Thru

Reserve online

Budtender Help

Call ahead or come see us

Recreational 21+

Shop with a valid ID

Medical 18+

Shop with a valid Med Card

Cash Payments

Old fashioned green

ATM Onsite

With a small fee

Debit Payments

With a small fee

Pay By Bank

Link your bank at checkout online

Free Parking Lot

With plenty of spots

Wheelchair Accessible

Parking and Entrance

About High Profile West Plains

High Profile’s West Plains dispensary is Missouri’s premier cannabis dispensary, offering premium medical marijuana products for every price point. Visit our West Plains location to check out our wide selection of flower, pre-rolls, edibles, concentrates, and more.

We are just off Highway 160 and near a number of local attractions, such as Health Haven Botanical Gardens and the Harlin Museum. As the leading medical marijuana dispensary in West Plains, Missouri, we provide premium medical cannabis products for every medical cardholder. Stop by and see us any day of the week from 8 AM -10 PM! We’re here and ready to help.

Shop at High Profile and Save

Save big every day at High Profile with competitive prices, discounted bundles, and fresh promos.
Shop All Discounts

Everyday discounts available in-store

10% off

Industry

Current cannabis industry employees

Wisdom

Age 60+

Student / Faculty

Active students and staff

First Time Customers

No strings attached
*Not stackable with other discounts or offers. Applicable in-store only.

5 for $50 Cloud Cover pre-rolls

Shop this everyday deal

3 for $99 featured distillate carts

Shop this everyday deal

2 for $55 Galactic 300mg gummies

Shop this everyday deal

What’s new

Get the scoop on all new and upcoming deals, promotions, and events.
Learn More

Roll with us

Earn rewards, unlock personalized promotions and early access. It’s good to be a High Roller.
Join Now

About High Profile

How our origin story is shaping our future. Learn about our No Assholes philosophy.
Learn More

Other High Profile Dispensaries in Missouri

Branson

3125 Green Mountain Dr, Branson, MO 65616 (417) 243-0622 Shop Now

Cape Girardeau

772 S Kingshighway #101, Cape Girardeau, MO 63703 (573) 381-2880 Shop Now

Chesterfield

42 Arnage Rd, Chesterfield, MO 63005 (636) 812-6569 Shop Now

Columbia

1500 Interstate 70 Dr SW Suites 1,2,3, Columbia, MO 65203 (573) 844-4007 Shop Now

Holland

80 State Hwy O, Steele, MO 63877 (573) 255-0342 Shop Now

Pineville

35 Macadoodle Ln, Pineville, MO 64856 (417) 202-0469 Shop Now

St Charles

1416 Harvestowne Industrial Dr, St Charles, MO 63304 (636) 224-6033 Shop Now

St Louis

10425 Watson Rd, St. Louis, MO 63127 (314) 353-9922 Shop Now

St Robert

231 St Robert Blvd, St Robert, MO 65584 (573) 586-4208 Shop Now

West Plains

1391 Mitchell Rd, West Plains, MO 65775 (417) 596-9086 Shop Now
high-profile-logo

Don’t miss another deal

By submitting, I agree to the Privacy Policy.

Shop

Save

Explore

Currently Shopping:

West Plains

1391 Mitchell Rd, West Plains, MO 65775
(417) 596-9086
8am - 10pm CT every day.
Download the High Profile App
Privacy Policy
Accessibility
Terms of Use
Disclaimers
Sitemap
Copyright © 2026 C3 Industries. All rights reserved. United States

Are you at least 21 years old or a valid medical patient?

By selecting 'Yes', you confirm that you are of legal age or a valid medical patient and agree to our Terms and Privacy Policy.

NO
Select a store
Use my current location

Store
Cape Girardeau, MO