











Missouri legalized recreational cannabis in November 2022 — and High Profile Cannabis has been St. Louis’s premium destination for it since day one. Find us at 10425 Watson Rd in Sunset Hills, right off I-44 on Historic Route 66, with 1,200+ tested and regulated cannabis products across every category. Whether you live in south St. Louis County, you’re passing through on the interstate, or you’re visiting from a state where cannabis is still off the table, this is where the experience starts.


With High Rollers Rewards signup

With valid Med Card

Thank you for your service

Current cannabis industry employees

Active students and staff

Thank you for your service
All customers age 60+
Missouri shares a border with eight states. Iowa, Kansas, Nebraska, Oklahoma, Arkansas, Tennessee, and Kentucky — seven of them have not legalized recreational cannabis. Illinois has, but most of the Midwest and South corridor heading through St. Louis hasn’t.
Missouri’s cannabis program is fully legal, state-regulated, and built for both residents and visitors. Every product on our shelves is tested, labeled, and licensed. If you’re in the state, you’re in legal territory — and High Profile in Sunset Hills is where St. Louis does it right.
Yes. Missouri voters approved Proposition 3 in November 2022, legalizing recreational adult-use cannabis. Sales began on February 3, 2023. Any adult 21 or older with a valid ID can purchase recreational cannabis in Missouri.
Yes. Any adult 21 or older with a valid government-issued photo ID can purchase recreational cannabis at High Profile Sunset Hills, regardless of which state they live in. No Missouri residency or medical card is required.
We're at 10425 Watson Rd in Sunset Hills — off I-44 Exit 277B (S. Lindbergh Blvd), east on Watson Rd. Watson Rd is Historic Route 66, and we'll be on your right heading east from Lindbergh.
Sunday through Thursday: 8 AM to 9 PM. Friday and Saturday: 8 AM to 10 PM. We're open every day, including most holidays — call ahead or check our website to confirm holiday hours.
We accept debit cards, Apple Pay, Google Pay, and cash. A majority of cannabis transactions are processed as debit or cash — we recommend having one of these ready when you arrive.
Yes. High Profile Sunset Hills offers special discounts for students, faculty, seniors, and veterans. Valid ID or documentation is required at the time of purchase. Daily deals are also available — check our online menu for current offers.
Yes. Browse our full live inventory and pre-order online for express in-store pickup at High Profile Sunset Hills. Ordering ahead saves time and ensures the products you want are ready when you walk in.




By selecting 'Yes', you confirm that you are of legal age or a valid medical patient and agree to our Terms and Privacy Policy.
