High Profile Cannabis Shop

Chesterfield

42 Arnage Rd, Chesterfield, MO 63005
(636) 812-6569
Open until 9:00pm (CT)
All hours
Mon
Tues
Wed
Thur
Fri
Sat
Sun
8:00am
-
9:00pm
8:00am
-
9:00pm
8:00am
-
9:00pm
8:00am
-
9:00pm
8:00am
-
10:00pm
8:00am
-
10:00pm
8:00am
-
9:00pm
Closing Early
09/22
8:00am - 8:00pm

Offered at High Profile Chesterfield

In-store Shopping

Drop in anytime

In-store Pickup

Reserve online

Drive Thru

Reserve online

Budtender Help

Call ahead or come see us

Recreational 21+

Shop with a valid ID

Medical 18+

Shop with a valid Med Card

Cash Payments

Old fashioned green

ATM Onsite

With a small fee

Pay By Bank

Link your bank at checkout online

Free Parking Lot

With plenty of spots

Wheelchair Accessible

Parking and Entrance

High Profile Chesterfield — Cannabis Dispensary in Chesterfield, MO

High Profile Chesterfield sits at 42 Arnage Rd in Chesterfield Valley, just off I-64/US-40 in the heart of West St. Louis County. This is a neighborhood dispensary first — familiar faces from the surrounding subdivisions, workers from St. Luke’s Hospital and the Bayer campus, and regulars from Ballwin, Ellisville, Town and Country, and the neighborhoods to the south and southeast who have made it their go-to stop. If you are stocking up before hitting other errands in the valley, High Profile is the stop worth making first — the menu runs the full range and the team keeps things moving.

Because the valley sits at the crossroads of the county, the store draws easily from the residential communities ringing it. Neighbors roll in from Ballwin, Ellisville, and Town and Country to the south and east, from Wildwood to the west, and from Creve Coeur and Maryland Heights closer to the city — most of them a 10-to-20-minute drive on Highway 40 or Manchester Road. The free parking lot, drive-thru, and online pickup make it easy to fold into the routine whether you are running a quick errand or doing a full shop.

Walk in and you are helped fast, whether you know exactly what you want or need a budtender to talk you through the flower, vapes, edibles, concentrates, and pre-rolls on the menu. Recreational shoppers 21+ are welcome with a valid ID, and medical patients are too.

Shop at High Profile and Save

Save big every day at High Profile with competitive prices, discounted bundles, and fresh promos.

Everyday discounts available in-store

20% off

First Time Customers

With High Rollers Rewards signup

1¢ pre-roll or edible

Second Visit

With High Rollers Rewards signup

15% off

Med Patients - Mon and Tues

With valid Med Card

Veterans - Tuesdays

Thank you for your service

10% off

Industry

Current cannabis industry employees

Student / Faculty

Active students and staff

Veterans

Thank you for your service

Wisdom 60+

All customers age 60+

*Not stackable with other discounts or offers. Applicable in-store only.

Serving West St. Louis County

High Profile Chesterfield serves the residential communities of West St. Louis County from its spot in Chesterfield Valley. The surrounding neighborhoods are close and easy to reach: Ellisville is about 7 miles south, Town and Country roughly 11 miles east along Highway 40, and Wildwood around 11 miles west. Shoppers coming from Ballwin, Creve Coeur, and Maryland Heights are all inside a 17-to-20-minute drive. The valley’s position at the I-64/US-40 corridor makes it the natural first stop for anyone moving through the west side of the county — with a full menu stocked for the kind of run that makes the most of Missouri’s purchasing limits.

What Our Customers Say About Us

Lee Newman
Lee Newman 3 weeks ago
★★★★★

Went into High Profile in Chesterfield looking for a specific terpene profile, not just whatever was popular, and Layne and Jake completely delivered. Neither of them pushed a particular brand or tried to rush me through the decision — they actually took the time to talk through terpene chemistry and help me land on something that matched what I was after. That level of product knowledge and patience is rare. I was impressed enough that I asked to speak with the manager on the spot to make sure it got noted. If you want budtenders who actually know cannabis science and aren't just running a sales script, ask for Layne or Jake. Easily the best dispensary experience I'v had.

jake gaby
jake gaby 1 month ago
★★★★★

Anabel was incredibly helpful and informative! I will definitely be back!!

Zac Cantor
Zac Cantor 2 months ago
★★★★★

Jake gaby was extremely friendly and welcoming. He was very knowledgeable and found me a great product based on what I described to him.He was also extremely patient when I left my debit card in the car. Overall the vibe in the store was out standing!

Andrew
Andrew 2 months ago
★★★★★

Needed a new place after moving back to town several months ago, decided to try this place out, and have been coming back ever since. Gray and the rest of the wonderful staff are very knowledgeable, and I have loved every recommendation they've suggested. I’m a regular because of the consistently excellent service I get—they even know me by name! I can't recommend them enough. 10/10.

GG
GG 2 months ago
★★★★★

Justin was super personable and helpful to find what I needed, great guy I think he should get a raise!

Jeff St Louis
Jeff St Louis 2 months ago
★★★★★

Great customer service

David Bosley
David Bosley 3 months ago
★★★★★

They made my first time a wonderful experience, very knowledgeable staff

Laura Gray
Laura Gray 3 months ago
★★★★★

Wes! You are the best ! Thanks for the selection and amazing service. Thanks for listening and getting us what we needed

Paco
Paco 3 months ago
★★★★★

I had an excellent experience at High Profile Dispensary. From the moment I walked in, everyone was welcoming, friendly, and professional. A special shoutout to Gray, the manager, who went above and beyond to make my visit enjoyable. She was incredibly kind, patient, and knowledgeable, taking the time to help me choose the perfect flower and pre rolls based on what I was looking for. The customer service was outstanding, and I never felt rushed or pressured. It’s clear that the team genuinely cares about their customers and wants them to have the best experience possible. I left feeling confident in my purchases and excited to come back. Highly recommend High Profile to anyone looking for quality products and exceptional service!

Leave a review.

Getting to High Profile Chesterfield in Chesterfield, MO

Ellisville, MO → High Profile Chesterfield (~7 miles | ~15 min)

Take MO-340 E/Clarkson Rd to Kehrs Mill Rd, follow it to Long Rd, turn right onto Chesterfield Airport Rd, then left onto Jaguar Land Rover Wy and left onto Arnage Rd — we'll be on your left.

Ballwin, MO → High Profile Chesterfield (~8 miles | ~18 min)

Take Holloway Rd to Kehrs Mill Rd and follow it into Chesterfield, then turn onto Jaguar Land Rover Wy and Arnage Rd — we'll be on your left.

Town and Country, MO → High Profile Chesterfield (~11 miles | ~17 min)

Get on I-64 W and take exit 17 for Boones Crossing in Chesterfield, then follow Chesterfield Airport Rd to Arnage Rd — we'll be on your left.

Wildwood, MO → High Profile Chesterfield (~11 miles | ~19 min)

Take MO-109 N to Missouri CC (Long Rd) and follow it into Chesterfield, then turn onto Jaguar Land Rover Wy and Arnage Rd — we'll be on your left.

Creve Coeur, MO → High Profile Chesterfield (~13 miles | ~17 min)

Get on I-270 S, merge onto I-64 W and take exit 17 for Boones Crossing in Chesterfield, then follow Chesterfield Airport Rd to Arnage Rd — we'll be on your left.

Maryland Heights, MO → High Profile Chesterfield (~16 miles | ~20 min)

Take Schuetz Rd to State Hwy D, get on I-270 S and merge onto I-64 W, take exit 17 for Boones Crossing, then follow Chesterfield Airport Rd to Arnage Rd — we'll be on your left.

FAQs about High Profile Chesterfield

High Profile Chesterfield is at 42 Arnage Rd, Chesterfield, MO 63005, in Chesterfield Valley just off I-64/US-40 near Chesterfield Commons. There is a free parking lot on-site with plenty of spots.

The store is open daily 8am–9pm Sunday through Thursday and 8am–10pm on Friday and Saturday (Central Time).

No — recreational customers 21 and older are welcome with a valid government-issued ID, and medical patients are served as well.

Yes — you can reserve online for in-store pickup or use the drive-thru, and in-store shopping with budtender help is available too.

The menu includes flower, pre-rolls, vapes, concentrates, and edibles from a rotating lineup of brands, with budtenders on hand to help you choose.

Still have a question? Reach out.
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Chesterfield

Chesterfield

Open until 9:00pm (CT)
42 Arnage Rd, Chesterfield, MO 63005
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