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High Profile West Plains sits at 1391 Mitchell Road on the north side of West Plains, right where Mitchell meets Bruce Smith Parkway on US-63 — the main corridor running south through the Ozarks toward Arkansas. This is one of the most stocked recreational menus in the south-central Ozarks, with a broader selection of brands and products than most stores in the region, which is why regulars drive from across North Central Arkansas and as far as Memphis to shop here.
Arkansas has no legal recreational cannabis, which means adults from Mountain Home, Batesville, Cherokee Village, and the surrounding North Central Arkansas hill country make the regular run north on US-63 without needing an Arkansas medical card or Missouri residency — just a valid government-issued ID for anyone 21 and over. Jonesboro, AR is roughly two hours south, and High Profile already has a regular customer base making that drive. Memphis-area shoppers have an added reason to make the trip now: Tennessee recently banned hemp-derived THC products, and West Plains is one of the most accessible full recreational destinations for drivers coming north out of the Memphis corridor. For customers crossing the border, the drive-thru makes it quick to grab an online or phone order without leaving the car.
West Plains also sits squarely in Ozark country, which means St. Louis-area visitors passing through on their way to the lakes and trails fold a stop into the trip. If you’re already making the drive into the Ozarks, this is the easiest place to stock up along the way.
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All customers age 60+
High Profile West Plains anchors the south-central Ozarks, drawing from a wide rural corridor that stretches from Howell County down through North Central Arkansas and east toward Memphis. Inside Missouri, the store draws regulars from Willow Springs, about 22 miles and 25 minutes northwest on US-63, and from Mountain View, roughly 30 miles and 35 minutes out via US-60 and US-63. Thayer, the last Missouri town before the border, is just 25 miles south and about 30 minutes down US-63. On the Arkansas side, Mountain Home is the closest major draw — a straight run up US-63 — followed by Batesville, Cherokee Village, and the broader North Central Arkansas communities that don’t have a recreational option closer to home. Jonesboro sits further south and east, and Memphis is roughly two and a half to three hours southeast on the highway. Whether you’re coming up from Arkansas, passing through on an Ozark trip, or making the longer run from Memphis, West Plains is the most stocked recreational stop in this corner of Missouri.
Mammoth Spring, AR is about 27 miles from High Profile West Plains, a roughly 40-minute drive north on US-63. West Plains is the first Missouri recreational stop once you cross the state line.
Yes. Any adult 21 or older with a valid government-issued photo ID can shop here — no Arkansas medical card and no Missouri residency required.
The store is about 16 miles north of the Missouri–Arkansas state line, located at 1391 Mitchell Road on the north side of West Plains.
No — recreational customers 21 and older are welcome with a valid government-issued ID.
Take US-63 North for about 27 miles through Thayer into West Plains, then turn onto Mitchell Road near Bruce Smith Parkway. The drive runs about 38 minutes.
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